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Teaching Activities

Organic Chemistry Lecturer, teaching activities

Undergraduate program

General Chemistry I and II, Organic chemistry I, Practical of organic- chemistry I, Organic chemistry II, Practical of Org chem. II, Molecular Determination Organic compound, Medicinal chemistry, Phytochemistry and Kapita selekta kimia organic


Magister program

Isolation of triterpeness and antibacterial activity



Doctoral program

Isolation of alkaloids and Anticancer  activity

Academic career




Bachelor Degree (Chemistry)          




FST Unair-Indonesia


Magister Degree (Organic Chemistry)



Doctoral Degree (Organic Chemistry)







Assistant professor



Associate Professor


2007 – now

Research and development projects overthelast5years

  1. Exploration of alkaloid contents from Erytrhina spp.  As inhibitor of Plasmodium Dihidrofolate Reductase (pDHFR) enzyme as antimalarial therapeutic target (2010, Ministry of Research and Education, and Police Instution, Rp. 150.000.000)
  2. Isolation of tuberospironine A, a novel croomine derivative from Stemona tuberosa Lour (2011, PAR DIKTI, Rp. 90.000.000)
  3. Alkaloid from ubi kemili hutan (S. tuberosa) as antifolat agent to dihydrofolat reductase (DHFR) enzyme inhibitor of Plasmodium falcifarum
  4. In vitro activity of chalcon and derivatives to the Fd/FNR Plasmodium falciparum (2013-2014, Ristek, Rp. 200.000.000)
  5. Alkaloid isolation from Stemona javanica (2014, BOPTN, 19.000.000)
  6. Alkaloid from S. tuberose as new antimalaria agents via inhibition mechanism of Feredoxin Reductase Fd/FNR- NADP+ P.falciparum (2015-2016,  Ministry of Research and Education, Rp. 100.000.000)
  7. Production of hard capsule shells from seaweed: drug release kinetic and pre-clinic test (2015-2016, Ministry of Research and Education,Rp. 250.000.000)
  8. Optimization of formula seaweed-starch for reducing cost of production (2016, Airlangga University,Rp.90..000.000)

Industry collaborations over the last 5 years

PT. Kapsulindo Nusantara, 2013-2016, Production of hard capsule shells from seaweed: drug release kinetic and pre-clinic test

Patents and proprietary rights



Production of hard capsule shells from seaweed

2016 (Register)

Production of hard capsule shells from seaweed and starch using natural color

2017 (Register)

Important publications over the last 5 years

  1. Pratiwi Pudjiastuti, Mat Ropi Mukhtar, A. Hamid . Hadi, Nurdin Saidi, Hiroshi Morita, Marc Litaudon, and Khalijah Awang, 6,7-Dimethoxy-4-methylisoquinolinyl)-(4’-methoxyphenyl)-methanone, A New Benzylisoquinoline Alkaloid from Beilschmiedia brevipes , Molecules, 2010, 15, 2339-2346
  2. Pratiwi Pudjiastuti, Stephen G. Phyne, Sugiyanto and Wilford Lie, Isolation of tuberospironine A, a novel croomine derivative from Stemona tuberosa Lour, Phytochemistry Letters 5 (2012)358-360
  3. Pratiwi Pudjiastuti, Sri Sumarsih, Heny Arwati, Ilma Amalina, Much. Z. Fanani, Edi P. Utomo, Loeki E. Fitri,Ari S. Nugraha, Wilford Lie and Stephen G. Pyne, Epi-croomine and croomine from Stemona tuberosa Lour as dihydrofolate reductase (DHFR)  inhibitors and their molecular modeling studies, Journal of Chemical  and Pharm Research, 2014, 6(6): 544-548
  4. Tjitjik Srie Tjahjandarie, Pratiwi Pudjiastuti, Ratih Dewi Saputri and Mulyadi Tanjung, Antimalarial and antioxidant activity of phenolic compounds isolated from Erythrina crista-galli L., Journal of Chemical  and Pharm Research, 2014, 6(4):786-790
  5. Hery Suwito, Jumina, Mustofa, Pratiwi Pudjiastuti, Much. Z. Fanani, Yoko Kimata-Ariga, Ritsuko Katahira, Toru kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat and Ni Nyoman Tri Puspaningsih, Design and Synthesis of Chalcone Derivatives as Inhibitors ofthe Ferredoxin — Ferredoxin-NADP+ Reductase Interaction of Plasmodium falciparum: Pursuing New Antimalarial Agents , Molecules,  2014, 19, 21473-21488
  6. Rosdayanti Alino Ramli, Pratiwi Pudjiastuti, Tjitjik Srie Tjahjandarie, Wilford Lie, Roonglawan Rattanajak, Sumalee Kamchonwongapaisan and Stephen G. Pyne, Alkaloids from the roots of Stemona javanica (Kunth) Engl. (Stemonaceae) and their anti-malarial, acetylcholinesterase inhibitory and cytotoxic activities, Phytochemistry Letters 11 (2015) 157-162
  7. Pratiwi Pudjiastuti, Rosmawaty, Sri Sumarsih, Heny Arwati, Ari S. Nugraha and , Loeki E. Fitri, In vitro study of parasitemia determination of alkaloids from S. tuberose Lour by flow cytometry in comparation with optical microscopy, Der Pharma Chemica, 2015, 7(10): 372-376

Activities in specialist bodies

Organization Role



Indonesia Chemical Society

Advisory Board