{"id":2204,"date":"2024-06-17T15:41:53","date_gmt":"2024-06-17T08:41:53","guid":{"rendered":"https:\/\/kimia.fst.unair.ac.id\/innovative-amino-acid-production-from-agricultural-biomass\/"},"modified":"2024-10-02T09:05:05","modified_gmt":"2024-10-02T02:05:05","slug":"innovative-amino-acid-production-from-agricultural-biomass","status":"publish","type":"post","link":"https:\/\/kimia.fst.unair.ac.id\/en\/innovative-amino-acid-production-from-agricultural-biomass\/","title":{"rendered":"Innovative Amino Acid Production from Agricultural Biomass"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2204\" class=\"elementor elementor-2204 elementor-954\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-598ca9dc elementor-section-height-min-height elementor-section-items-top elementor-section-boxed elementor-section-height-default\" data-id=\"598ca9dc\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wide\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-3b6d985a\" data-id=\"3b6d985a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7da06b89 elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"7da06b89\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Innovative Amino Acid Production from Agricultural Biomass<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-175f03a1 elementor-widget elementor-widget-post-info\" data-id=\"175f03a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-734f236 elementor-inline-item\" itemprop=\"author\">\n\t\t\t\t\t\t<a href=\"https:\/\/kimia.fst.unair.ac.id\/en\/author\/editor1\/\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-user-circle\" viewBox=\"0 0 496 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M248 104c-53 0-96 43-96 96s43 96 96 96 96-43 96-96-43-96-96-96zm0 144c-26.5 0-48-21.5-48-48s21.5-48 48-48 48 21.5 48 48-21.5 48-48 48zm0-240C111 8 0 119 0 256s111 248 248 248 248-111 248-248S385 8 248 8zm0 448c-49.7 0-95.1-18.3-130.1-48.4 14.9-23 40.4-38.6 69.6-39.5 20.8 6.4 40.6 9.6 60.5 9.6s39.7-3.1 60.5-9.6c29.2 1 54.7 16.5 69.6 39.5-35 30.1-80.4 48.4-130.1 48.4zm162.7-84.1c-24.4-31.4-62.1-51.9-105.1-51.9-10.2 0-26 9.6-57.6 9.6-31.5 0-47.4-9.6-57.6-9.6-42.9 0-80.6 20.5-105.1 51.9C61.9 339.2 48 299.2 48 256c0-110.3 89.7-200 200-200s200 89.7 200 200c0 43.2-13.9 83.2-37.3 115.9z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-author\">\n\t\t\t\t\t\t\t\t\t\tEditor Satu\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-5f053c5 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/kimia.fst.unair.ac.id\/en\/2024\/06\/17\/\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>June 17, 2024<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-638fe3f2 elementor-widget elementor-widget-image\" data-id=\"638fe3f2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"902\" src=\"https:\/\/kimia.fst.unair.ac.id\/wp-content\/uploads\/sites\/19\/2024\/06\/Ilustrasi-makanan-penghasil-asam-amino.jpg\" class=\"attachment-full size-full wp-image-956\" alt=\"\" srcset=\"https:\/\/kimia.fst.unair.ac.id\/wp-content\/uploads\/sites\/19\/2024\/06\/Ilustrasi-makanan-penghasil-asam-amino.jpg 1200w, https:\/\/kimia.fst.unair.ac.id\/wp-content\/uploads\/sites\/19\/2024\/06\/Ilustrasi-makanan-penghasil-asam-amino-300x226.jpg 300w, https:\/\/kimia.fst.unair.ac.id\/wp-content\/uploads\/sites\/19\/2024\/06\/Ilustrasi-makanan-penghasil-asam-amino-1024x770.jpg 1024w, https:\/\/kimia.fst.unair.ac.id\/wp-content\/uploads\/sites\/19\/2024\/06\/Ilustrasi-makanan-penghasil-asam-amino-768x577.jpg 768w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Illustration of Amino Acid Producing Foods (Image: PYFA Health)<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4e46da31 elementor-widget elementor-widget-text-editor\" data-id=\"4e46da31\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>As the world&#8217;s population grows, the agricultural sector continues to expand to meet the growing demand for food. Currently, around 23.7 million tonnes of food is produced every day from the agricultural sector. By 2050, food production is expected to increase from 8.4 billion tonnes to 13.4 billion tonnes per year. However, this development of the agricultural industry has also led to an increasing amount of waste being generated.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2bc57f99 elementor-widget elementor-widget-text-editor\" data-id=\"2bc57f99\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Agriculture in Indonesia and Malaysia produces large amounts of waste that needs to be managed to address environmental issues. These wastes generally have high starch and lignocellulose content, and have the potential to be utilised for the development of value-added products, such as amino acid production. Traditional methods often rely on expensive commercial enzymes to convert biomass into fermentable sugars for amino acid production. An alternative, consolidated bioprocessing, enables the direct conversion of agricultural biomass into amino acids using selected microorganisms. This review provides a comprehensive assessment of the potential of agricultural biomass in Indonesia and Malaysia for amino acid production via consolidated bioprocessing, through the use of suitable microorganisms.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-52e0736 elementor-widget elementor-widget-text-editor\" data-id=\"52e0736\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Consolidated Bioprocessing (CBP) is a process that combines enzyme production, saccharification and fermentation into a single step. This approach reduces costs and increases productivity, making it popular for producing low-cost and value-added products. However, finding microbes that can perform all the necessary processes in one step is a challenge. Often, bacteria are the best choice as they can produce the required amino acids and enzymes.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-79be2d6 elementor-widget elementor-widget-text-editor\" data-id=\"79be2d6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Different types of bacteria have different capabilities. For example, some strains of Escherichia coli can make methionine and tryptophan, while Bacillus subtilis is able to make lysine. Optimising fermentation conditions, such as temperature and agitation, is also important to improve efficiency.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fb77a9f elementor-widget elementor-widget-text-editor\" data-id=\"fb77a9f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The use of processed raw materials, such as maize stover and pineapple plant stalks, can also help make the process more sustainable. This highlights the need for innovation and optimisation to meet the growing demand for low-cost and sustainable production. Different types of bacteria, including E. coli, B. subtilis, Corynebacterium glutamicum and Pediococcus species, have unique metabolic capabilities that can adapt to different feedstock substrates.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ce382b9 elementor-widget elementor-widget-text-editor\" data-id=\"ce382b9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The flexibility of bacteria to use different feedstocks, such as glucose, molasses, soybean meal, corn stover, and pineapple plant stalk, supports the flexibility of CBP in amino acid production. However, the amount of amino acids produced varies between microbial strains and feedstock substrates, so process optimisation is important. In a study conducted by Li et al. (2022), starch was used as the main feedstock for l-lysine production through genetic engineering of C. glutamicum strain KT45-6S-5, which produced 23.9 g\/L lysine.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c6ecc9 elementor-widget elementor-widget-text-editor\" data-id=\"3c6ecc9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The use of microorganism co-cultures involving B. subtilis, C. glutamicum or E. coli for amino acid production from agricultural biomass shows great potential in improving process efficiency and yield through consolidated bioprocessing. However, research is needed to study its feasibility and understand the benefits and limitations of co-culture systems in the amino acid industry, as well as their optimization for process improvement.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-01e6528 elementor-widget elementor-widget-text-editor\" data-id=\"01e6528\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>This article contributes to the advancement of sustainable amino acid production methods using agricultural biomass specifically through bioprocess consolidation, waste reduction, and improved environmental sustainability.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8f44c47 elementor-widget elementor-widget-text-editor\" data-id=\"8f44c47\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Keywords: Amino acid production, agricultural waste, consolidated bioprocessing<\/p>\n<p>Source: Pei-Hsia Chu, Mohd Azwan Jenol, Lai-Yee Phang, Mohamad Faizal Ibrahim, Purkan Purkan, Sofjan Hadi, Suraini Abd-Aziz. Innovative approaches for amino acid production via consolidated bioprocessing of agricultural biomass. Environmental Science and Pollution Research, 2024. Vol 31. Issue 21. https:\/\/doi.org\/10.1007\/s11356-024-33534-0<\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-11c9b054\" data-id=\"11c9b054\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-320eabd elementor-widget elementor-widget-heading\" data-id=\"320eabd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Other News<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2971705f elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"2971705f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Illustration of Amino Acid Producing Foods (Image: PYFA Health) As the world&#8217;s population grows, the agricultural sector continues to expand to meet the growing demand for food. Currently, around 23.7 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":956,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[],"class_list":["post-2204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-of"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Innovative Amino Acid Production from Agricultural Biomass - S1 Kimia Fakultas Sains dan Teknologi Universitas Airlangga<\/title>\n<meta name=\"description\" content=\"The use of B. subtilis, C. glutamicum or E. coli for amino acid production from agricultural biomass can improve process efficiency and yield through consolidated bioprocessing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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